Ama-oxalates alungile ebantwini abanengi, kodwana abantu abanokusebenza kwamathumbu atjhugulukileko bangafuna ukunciphisa ukudla kwabo. Irhubhululo alitjengisi bona ama-oxalate abangela i-autism nofana ubuhlungu obungapheliko besitho sangasese sowesifazane, kodwana angakhuphula ubungozi bamatshe wezinso kwabanye abantu.
I-oxalic acid yi-organic acid etholakala eentjalweni ezinengi, okufakahlangana amaqabunga ahlaza, imirorho, iinthelo, i-cocoa, amantongomani, kanye nembewu (1).
Eentjalweni, kanengi ihlangana namaminerali ukwakha ama-oxalate. Amagama athi "oxalic acid" kanye "noxalate" asetjenziswa ngokufana kwezesayensi yokudla.
Umzimba wakho ungakhiqiza ama-oxalates ngokwawo nofana uwathole ngokudla. Ivithamini C nayo ingatjhugululwa ibe yi-oxalate ngokusebenzisa umzimba (2).
Lokha nayithathwa, ama-oxalate angahlangana namaminerali ukwakha amakhompawundi afakahlangana i-calcium oxalate kanye ne-iron oxalate. Kwenzeka khulu emathunjini, kodwana kungenzeka nasezinsoni nakwezinye iindawo zomgudu womchamo.
Kodwana, ebantwini abazwelako, ukudla okunama-oxalates amanengi kungakhuphula ubungozi bamatshe wezinso neminye imiraro yezamaphilo.
I-Oxalate yi-esidi ye-organic etholakala eentjalweni, kodwana ingenziwa mzimba. Ihlangana namaminerali begodu ihlotjaniswa nokwakheka kwamatje wezinso neminye imiraro yezamaphilo.
Okhunye ukutshwenyeka okukhulu kwezamaphilo okuhlobene nama-oxalates kukobana angabophelela emamineralini emathunjini begodu avimbele bona angamunwa mzimba.
Ukwenza isibonelo, isipinatjhi sinothile nge-calcium kanye nama-oxalates, okuvimbela umzimba bona umunce inani elikhulu le-calcium (4).
Kodwana, kuqakathekile ukukhumbula bona ngamanye amaminerali ekudleni abophelela kuma-oxalates.
Nanyana ukumuncwa kwe-calcium evela esipinatjhi kwehlile, ukudla ibisi nesipinatjhi ndawonye akuthinti ukumuncwa kwe-calcium evela ebisi (4).
Ama-oxalates angabophelela emamineralini emathunjini begodu aphazamise ukumunywa kwamanye wawo, khulukhulu lokha nakahlanganiswa nefayibha.
Ngokuvamileko, i-calcium kanye ne-oxalate encani zikhona ndawonye emgudwini womchamo, kodwana zihlala zincibilikile begodu azibanga imiraro.
Kodwana, kesinye isikhathi ziyahlangana enze amakristalu. Kwabanye abantu, amakristalu la angadosela ekwakhiweni kwamatje, khulukhulu nangabe amazinga we-oxalate aphezulu begodu ukuphuma komnthondo kuphasi (1).
Amatje amancani kanengi awabangeli imiraro, kodwana amatje amakhulu angabanga ubuhlungu obukhulu, isicanucanu, kanye neengazi emchameni njengombana zidlula emgudwini womchamo.
Ngalokho-ke, abantu abanomlando wamatje weenso bangayeleliswa bona banciphise ukudla kwabo okunama-oxalates amanengi (7, 8).
Kodwana, ukuvinjelwa okupheleleko kwe-oxalate akusakhuthazwa kizo zoke iingulani ezinamatje wezinso. Lokhu kungenxa yokuthi ingcenye ye-oxalate etholakala emchameni ikhiqizwa mzimba kunokobana idonswe ngokudla (8, 9).
Inengi labodorhodera be-urologist njenganje libeka ukudla okuqinileko okune-oxalate encani (ngaphasi kwe-100 mg ngelanga) kwaphela eengulini ezinamazinga aphezulu we-oxalate emchameni (10, 11).
Ngalokho-ke, kuqakathekile ukuhlola ngeenkhathi ezithileko ukuthola bona kutlhogeka ukuvinjelwa okungakanani.
Ukudla okune-oxalates enengi kungakhuphula ubungozi bamatshe wezinso ebantwini abasengozini. Iincomo zokunciphisa ukuthatha i-oxalate zisekelwe emazingeni we-oxalate emchameni.
Abanye baveza bona ama-oxalates angahlotjaniswa ne-vulvodynia, ebonakala ngobuhlungu obungapheliko, obungahlathululiwe.
Ngokuya ngemiphumela yocwaningo, abarhubhululi bakholelwa bona zombili iimeko akunakwenzeka bona zibangelwe ma-oxalates wokudla (12, 13, 14).
Kodwana, esifundweni sango-1997 lapho abafazi abama-59 abane-vulvodynia balatjhwa ngokudla okune-oxalate encani kanye nezithasiselo ze-calcium, pheze ikota yathola ukuthuthuka kweempawu (14).
Abatloli bephenyo baphetha ngokuthi ama-oxalate wokudla angathuthukisa kunokobana abangele ubulwele.
Ezinye iindaba eziku-inthanethi zihlobanisa ama-oxalates ne-autism nofana i-vulvodynia, kodwana zimbalwa iimfundo ezihlolisise ukuhlobana okungenzeka. Irhubhululo elinabileko liyatlhogeka.
Abanye abantu bakholelwa bona ukudla ukudla okune-oxalates enengi kungabangela i-autism nofana i-vulvodynia, kodwana irhubhululo lamanje alisekeli iinsolo lezi.
Abanye abasekeli bokudla okune-oxalate encani bathi kungcono bona abantu bagweme ukudla okune-oxalate ngombana kungaba nemiphumela emimbi epilweni.
Kodwana, yoke into ayilula kangako. Okunengi kokudla lokhu kunepilo begodu kunama-antioxidant aqakathekileko, ifayibha, nezinye izakhamzimba.
Ukudla okunengi okune-oxalates kumnandi begodu kunepilo. Ebantwini abanengi, ukuzibalekela akutlhogeki begodu kungaba yingozi.
Amanye ama-oxalate owadlako aphulwa mabhaktheriya asemathunjini wakho ngaphambi kobana ahlanganiswe namaminerali.
Elinye lamabhaktheriya, i-Oxalobacterium oxytogenes, isebenzisa i-oxalate njengomthombo wamandla. Lokhu kwehlisa khulu inani le-oxalate edonswa mzimba (15).
Kodwana, abanye abantu abanawo amagciwani amanengi emathunjini wabo ngombana ama-anthibhayothiki anciphisa inani lamakoloni we-O. formigenes (16).
Ukungezelela, iimfundo zitjengise bona abantu abanesifo sokuvuvuka kwamathumbu banengozi ephezulu yokuthola amatje wezinso (17, 18).
Ngokufanako, amazinga aphakemeko we-oxalate atholakele emchameni wabantu abakhe bahlinzwa nge-gastric bypass nofana ezinye iinkambiso ezitjhugulula ukusebenza kwamathumbu (19).
Lokhu kuveza bona abantu abathatha ama-anthibhayothikhi nofana abanokungasebenzi kuhle kwamathumbu bangazuza khulu ngokudla okune-oxalate encani.
Inengi labantu abaphilileko lingadla ukudla okune-oxalates ngaphandle kwemiraro, kodwana abantu abanokusebenza kwamathumbu okutjhugulukileko bangatlhoga ukunciphisa ukudla kwabo.
Ama-oxalates atholakala pheze kizo zoke iintjalo, kodwana ezinye ziqukethe inani elikhulu khulu kuthi ezinye ziqukethe inani elincani khulu (20).
Ubukhulu bokuphakela bungahluka, okutjho bona ezinye ukudla “okune-oxalate enengi”, njenge-chicory, kungathathwa njengokudla okune-oxalate ephasi nangabe ubukhulu bokuphakela buncani ngokwaneleko. Nanzi irhelo lokudla okune-oxalates enengi (ngaphezu kwama-50 mg nge-100-gram) (21, 22, 23, 24, 25):
Inani le-oxalate eentjalweni lisuka phezulu khulu ukuya phasi khulu. Ukudla okune-oxalates engaphezu kwama-50 milligrams ngesivinini ngasinye kuhlukaniswa njenge "oxalate ephezulu."
Abantu abadla ukudla okune-oxalate encani ngebanga lamatshe eenso bavamise ukucelwa bona badle ngaphasi kwamamiligremu ama-50 we-oxalate ngelanga.
Ukudla okulinganiselweko nokunomsoco kungatholwa ngokuqukethwe kwe-oxalate kwangamalanga okungaphasi kwama-50 mg. I-calcium nayo isiza ukwehlisa ukumunywa kwama-oxalates.
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